Rabies diagnostic criteria

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Iqra Qamar M.D.[2]

Overview

Rabies is a clinical diagnosis that includes a thorough medical history and a high degree of suspicion. Laboratory findings that help with the diagnosis of rabies include skin biopsy specimens showing virus-specific immunofluorescent staining, isolation of virus from the samples of saliva and detection of anti-rabies antibodies in serum or cerebrospinal fluid (CSF).

Diagnostic Criteria

The diagnosis of rabies is made on the basis of clinical and laboratory findings.

References

  1. Venkatesan A, Tunkel AR, Bloch KC, Lauring AS, Sejvar J, Bitnun A, Stahl JP, Mailles A, Drebot M, Rupprecht CE, Yoder J, Cope JR, Wilson MR, Whitley RJ, Sullivan J, Granerod J, Jones C, Eastwood K, Ward KN, Durrheim DN, Solbrig MV, Guo-Dong L, Glaser CA (2013). "Case definitions, diagnostic algorithms, and priorities in encephalitis: consensus statement of the international encephalitis consortium". Clin. Infect. Dis. 57 (8): 1114–28. doi:10.1093/cid/cit458. PMC 3783060. PMID 23861361.
  2. Rupprecht CE, Hanlon CA, Hemachudha T (2002). "Rabies re-examined". Lancet Infect Dis. 2 (6): 327–43. PMID 12144896.

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